This inventor holds 1 USPTO granted patent and 2 published patent applications and 1 EPO patent. Top assignees: National Cheng-Kung University, University of California. Active years: 2026.
Company Filing History:

Years Active: 2026
Title: Innovations by Li-Hsien Chen in Bioelectric Neuromodulation
Introduction
Li-Hsien Chen is a notable inventor based in Tainan, Taiwan. He has made significant contributions to the field of bioelectric neuromodulation, particularly in the context of enhancing hematopoiesis during chemotherapy treatments. His innovative approach aims to mitigate the negative impacts of chemotherapy on blood cell production.
Latest Patents
Li-Hsien Chen holds a patent for a device and method titled "Bioelectric neuromodulation for hematopoiesis regulation during chemotherapy." This invention involves stimulating sympathetic nerves to improve hematopoiesis. The system includes an autonomic nerve actuator and stimulator, which utilizes a graphic user interface (GUI) and a controller circuit. This circuit converts treatment parameters into a series of Building Block Waveforms (BBW) that are output to Current/Voltage Driver Circuitry (CDC). The electrical stimulus outputs are coupled to electrodes positioned near specific nerve locations. The combination of this device with conventional chemotherapy, such as carboplatin, has shown significant enhancements in hematopoiesis, leading to improved blood cell counts and increased survival rates in experimental groups.
Career Highlights
Throughout his career, Li-Hsien Chen has worked with prestigious institutions, including the University of California and National Cheng-Kung University. His work has been instrumental in advancing the understanding and application of bioelectric neuromodulation in medical treatments.
Collaborations
Li-Hsien Chen has collaborated with notable colleagues, including Meng-Ru Shen and Wentai Liu. These partnerships have contributed to the development and refinement of his innovative technologies.
Conclusion
Li-Hsien Chen's contributions to bioelectric neuromodulation represent a significant advancement in medical technology, particularly for patients undergoing chemotherapy. His innovative patent demonstrates the potential for improving patient outcomes through targeted nerve stimulation.