Li-Chien Chang

Title: Innovations in Oral Drug Administration by Li-Chien Chang

Introduction

Li-Chien Chang is a notable inventor based in Taipei, Taiwan. He has made significant contributions to the field of pharmaceuticals, particularly in the area of drug delivery systems. His innovative work focuses on improving the oral administration of drugs that are typically unstable or poorly absorbed.

Latest Patents

Li-Chien Chang holds a patent for the "Oral administration of unstable or poorly-absorbed drugs." This patent describes dosage forms and combinations that facilitate effective oral administration of drugs unsuitable for this route due to degradation caused by acid and digestive enzymes. The invention includes a self-microemulsifying drug delivery system (SMEDDS) combined with an antacid. This formulation can prevent drug degradation in the gastric environment and enhance the absorption of water-soluble drugs in the gastrointestinal tract. Notably, this system can be used to administer insulin orally, allowing for long-term storage in powder form that can be reconstituted before use.

Career Highlights

Li-Chien Chang is associated with Innopharmax, Inc., where he continues to develop innovative solutions in drug delivery. His work has the potential to revolutionize how certain medications are administered, making them more accessible and effective for patients.

Collaborations

Li-Chien Chang collaborates with talented individuals such as Yu-Tsai Yang and Jong-Jing Wang, contributing to a dynamic research environment that fosters innovation.

Conclusion

Li-Chien Chang's contributions to the field of oral drug administration highlight the importance of innovation in pharmaceuticals. His patent for improving drug delivery systems demonstrates a commitment to enhancing patient care through scientific advancements.