Company Filing History:
Years Active: 2017
Title: Innovations of Leyi Wang in Immunogenicity Enhancement
Introduction
Leyi Wang is an accomplished inventor based in Cincinnati, OH (US). She has made significant contributions to the field of immunology through her innovative research and patent work. Her focus on protein complex systems has the potential to revolutionize vaccine development and enhance immune responses.
Latest Patents
Leyi Wang holds a patent titled "Protein complex system for increased immunogenicity and functionality, and methods making and use." This patent describes a groundbreaking approach where genes for proteins that spontaneously form dimers and/or oligomers are recombinantly linked together. Upon expression, these genes produce stable dimeric fusion proteins that self-assemble into large, polyvalent complexes. These complexes exhibit increased immunogenicity and functionality compared to individual proteins. The patent outlines the construction of linear, network, and agglomerate complexes using various proteins, including glutathione S-transferase and Norovirus P domains. The resulting complexes can contain hundreds to thousands of protein copies, making them promising candidates for bivalent or multivalent vaccines against Norovirus and other pathogens.
Career Highlights
Leyi Wang is currently affiliated with the Children's Hospital Medical Center, where she continues her research and development efforts. Her work has garnered attention for its innovative approach to enhancing vaccine efficacy and immune response.
Collaborations
Leyi collaborates with notable colleagues, including Ming Tan and Xi Jason Jiang, who contribute to her research endeavors. Their combined expertise fosters a collaborative environment that drives innovation in immunology.
Conclusion
Leyi Wang's contributions to the field of immunology through her patent on protein complex systems highlight her innovative spirit and dedication to advancing vaccine technology. Her work has the potential to significantly impact public health by improving immunogenicity and functionality in vaccine development.