Company Filing History:
Years Active: 2022-2025
Title: Letha Chemmalil: Innovator in Protein Analysis
Introduction
Letha Chemmalil is a prominent inventor based in Devens, MA (US). She has made significant contributions to the field of protein analysis, particularly in the characterization of PEGylated proteins. With a total of 2 patents, her work has advanced the methodologies used in biopharmaceutical research.
Latest Patents
One of her latest patents is focused on an isoelectric focusing sample matrix. This innovation provides icIEF sample matrices that enable the analysis of PEGylated proteins in their real conjugated states. The matrices include glycine, which facilitates the separation of co-migrated PEGylated protein charge variants. Additionally, the inclusion of taurine improves the icIEF assay by reducing matrix-induced baseline interferences. This combination allows for the effective identification, separation, characterization, and quantification of discrete PEGylated protein species. Another notable patent involves a method for determining the glycan moiety on recombinant glycoproteins using condensation nucleation light scattering detection.
Career Highlights
Throughout her career, Letha has worked with leading companies in the biopharmaceutical industry, including Amgen Inc. and Bristol-Myers Squibb Company. Her expertise in protein analysis has made her a valuable asset in these organizations.
Collaborations
Letha has collaborated with notable professionals in her field, including Zhengjian Li and Xin Zhang. These partnerships have contributed to her innovative research and development efforts.
Conclusion
Letha Chemmalil's contributions to the field of protein analysis through her patents and collaborations highlight her role as a leading inventor. Her work continues to influence the methodologies used in biopharmaceutical research and development.