Johnston, IA, United States of America

Leszek Alexander Lyznik



Average Co-Inventor Count = 4.4

ph-index = 7

Forward Citations = 200(Granted Patents)


Company Filing History:


Years Active: 2001-2008

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8 patents (USPTO):

Title: Leszek Alexander Lyznik: Innovator in Plant Genetic Engineering

Introduction

Leszek Alexander Lyznik is a prominent inventor based in Johnston, IA (US). He has made significant contributions to the field of plant genetic engineering, holding a total of 8 patents. His work focuses on innovative methods for mobilizing viral genomes and integrating foreign DNA into eukaryotic genomes.

Latest Patents

Lyznik's latest patents include groundbreaking inventions such as the "Mobilization of viral genomes from T-DNA using site-specific recombination systems." This invention relates to methods and compositions for the site-specific recombinase-mediated mobilization of viral replicons and associated DNAs from T-DNA. The methods involve transferring T-DNA to a plant cell, which contains a viral replicon flanked by target sites for a site-specific recombinase. The expression of the recombinase in the plant cell leads to the excision of the viral replicon and the associated DNA of interest, allowing for high copy number replication in the host plant cell.

Another notable patent is the "Method for the integration of foreign DNA into eukaryotic genomes." This invention provides compositions and methods for introducing a DNA of interest into a genomic target site. The methods utilize a combination of target sites for two site-specific recombinases and the expression of a chimeric recombinase with dual target site specificity. This results in efficient targeted genomic integration of DNA by site-specific recombination, particularly in plant cells.

Career Highlights

Lyznik is currently employed at Pioneer Hi-Bred International, Inc., where he continues to advance research in plant genetics. His innovative approaches have positioned him as a key figure in the field, contributing to the development of new techniques for genetic modification.

Collaborations

Throughout his career, Lyznik has collaborated with notable colleagues, including Christopher L Baszczynski and William James Gordon-Kamm. These collaborations have further enhanced the impact of his research and innovations in plant genetic engineering.

Conclusion

Leszek Alexander Lyznik is a distinguished inventor whose work in plant genetic engineering has led to significant advancements in the field. His innovative patents and contributions continue to shape the future of genetic research and applications in agriculture.

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