Lester Smith

Title: Lester Smith - Innovator in Collagen Matrix Technology

Introduction

Lester Smith is a notable inventor based in St. Louis, MO (US). He has made significant contributions to the field of biomedical engineering, particularly in the development of advanced collagen matrices. His innovative work focuses on enhancing tissue regeneration and cell infiltration through improved material properties.

Latest Patents

Lester Smith holds a patent for a "Collagen matrix with locally controlled intrafibrillar and extrafibrillar mineral content and methods of producing." This patent describes a mineralized collagen matrix that features an intrafibrillar and/or extrafibrillar gradient of mineralization, which is crucial for insertion replacement applications. The addition of fetuin to simulated body fluid facilitates the intrafibrillar mineralization of the collagen matrix. This gradient not only stiffens the matrix but also simulates a natural insertion, thereby promoting better cell infiltration and regeneration.

Career Highlights

Lester Smith is affiliated with Washington University, where he continues to advance research in biomaterials. His work has implications for various medical applications, particularly in regenerative medicine and tissue engineering. His innovative approach to collagen matrix development showcases his commitment to improving patient outcomes through scientific research.

Collaborations

Lester collaborates with esteemed colleagues in his field, including Stavros Thomopoulos. Their joint efforts contribute to the advancement of knowledge and technology in the area of biomaterials.

Conclusion

Lester Smith's contributions to collagen matrix technology exemplify the impact of innovative research in biomedical engineering. His patent and ongoing work at Washington University highlight the importance of developing materials that enhance tissue regeneration and improve medical treatments.