Location History:
- Cary, NC (US) (1997 - 1998)
- Apex, NC (US) (1998 - 2000)
Company Filing History:
5 out of 126 
2 out of 166 
1 out of 6,850 
Years Active: 1997-2000
Title: The Innovations of Leslie B Friedrich
Introduction
Leslie B Friedrich is a prominent inventor based in Cary, NC (US). She has made significant contributions to the field of plant biotechnology, holding a total of 9 patents. Her work focuses on enhancing disease resistance in plants through innovative genetic methods.
Latest Patents
One of her latest patents is titled "Gene encoding a protein involved in the signal transduction cascade." This invention concerns the location and characterization of a gene designated NIM1, which is a key component of the SAR pathway. This gene, in connection with chemical and biological inducers, enables the induction of SAR gene expression and broad-spectrum disease resistance in plants. The invention also includes transformation vectors and processes for overexpressing the NIM1 gene in plants, resulting in transgenic plants with broad-spectrum disease resistance.
Another notable patent is the "Method for protecting plants." This invention outlines a method of protecting plants from pathogen attacks through synergistic disease resistance. This is achieved by applying a conventional microbicide to immunomodulated plants, which are those in which SAR is activated. The method provides several ways to create immunomodulated plants, including the application of chemical inducers or through selective breeding programs. The concurrent application of a microbicide to these plants unexpectedly enhances disease resistance beyond expected levels.
Career Highlights
Leslie has worked with notable companies such as Novartis Finance Corporation and Novartis Corporation. Her experience in these organizations has contributed to her expertise in plant biotechnology and innovation.
Collaborations
Throughout her career, Leslie has collaborated with esteemed colleagues, including John A Ryals and Scott Joseph Uknes. These partnerships have furthered her research and development efforts in the field.
Conclusion
Leslie B Friedrich's innovative work in plant biotechnology has led to significant advancements in disease resistance through her patented inventions. Her contributions continue to impact the agricultural sector positively.