Lexington, KY, United States of America

Leonidas G Bachas

USPTO Granted Patents = 10 

Average Co-Inventor Count = 4.4

ph-index = 4

Forward Citations = 48(Granted Patents)


Location History:

  • Lextington, KY (US) (2000)
  • Lexington, KY (US) (1999 - 2009)

Company Filing History:


Years Active: 1999-2009

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10 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Leonidas G. Bachas

Introduction

Leonidas G. Bachas is a prominent inventor based in Lexington, KY (US), known for his significant contributions to the field of biotechnology. With a total of 10 patents, his work focuses on developing innovative solutions for high-throughput screening and cancer detection.

Latest Patents

One of his latest patents involves stimuli-responsive hydrogel microdomes integrated with genetically engineered proteins for high-throughput screening of pharmaceuticals. This invention features a hydrogel microdome that can swell in response to stimuli or target molecules, formed by polymerizing a mixture of a monomer capable of forming a hydrogel with a biopolymer. An array of these hydrogel microdomes can be created on a substrate through microspotting and polymerization, allowing for high-throughput screening of analytes, as well as functioning as actuators and biosensors due to the swelling properties of the hydrogel.

Another notable patent pertains to methods for cancer detection. This method utilizes the ability of an analyte to induce permeability in a barrier, providing a biosensor that includes a barrier substantially impermeable to an ion, a permeable membrane selective for the ion, and a detector capable of detecting the ion. When the biosensor is contacted with a sample containing the ion and the analyte, the analyte facilitates the passage of the ion through the barrier and membrane, enabling indirect detection of the analyte.

Career Highlights

Leonidas G. Bachas has worked with esteemed institutions such as the University of Kentucky Research Foundation and the University of California. His research has significantly advanced the understanding and application of biosensors and hydrogels in medical diagnostics.

Collaborations

Throughout his career, Bachas has collaborated with notable colleagues, including Dibakar Bhattacharyya and Jamie A. Hestekin. These partnerships have fostered innovation and contributed to the success of his research endeavors.

Conclusion

Leonidas G. Bachas exemplifies the spirit of innovation in biotechnology through his patents and research contributions. His work continues to impact the fields of pharmaceuticals and cancer detection, showcasing the importance of inventive thinking in addressing complex medical challenges.

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