This inventor holds 9 USPTO granted patents. Top assignees: Merck + Co., Inc., Columbia University, The State University of New York. Active years: 1996-2003.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Scoth Plains, NJ (US) (1999)
- Scotch Plains, NJ (US) (1996 - 2003)
Company Filing History:
7 out of 4,770 
2 out of 2,560 
1 out of 2,046 
Years Active: 1996-2003
Title: Innovations of Leonardus H Van Der Ploeg: Pioneering Advances in Molecular Biology
Introduction:
Leonardus H Van Der Ploeg, a distinguished inventor based in Scotch Plains, NJ, holds an impressive portfolio of nine patents. His contributions to molecular biology and biochemistry have positioned him as a key figure in the field, particularly through his innovative approaches to receptor technology and assays.
Latest Patents:
Among his latest patents, the creation of mutant OB receptors and the development of a leptin assay stand out. The mutant OB receptors he developed are characterized by specific modifications:
a) They lack a functional first CK-F3 domain.
b) They lack a functional second CK-F3 domain.
c) They lack a functional intracellular domain.
These receptors offer significant potential in various assays, including a transactivation assay designed to identify novel ligands. His invention of a leptin assay enhances the understanding of leptin's role in metabolism. It describes a trans-activation process where leptin binds to its receptor, leading to the transcription of a reporter gene linked to the promoter, which contains leptin response elements.
Career Highlights:
Leonardus has had a notable career, working with prominent organizations such as Merck & Company, Inc. and Columbia University. His role in these institutions has facilitated numerous groundbreaking research initiatives and has contributed to advancements in pharmacology and biotechnology.
Collaborations:
Collaboration has played a significant role in Leonardus' career. He has worked alongside esteemed colleagues like Jeffrey W Warmke and Doris B Tse, which has fostered an environment of innovation and mutual learning in their projects.
Conclusion:
Leonardus H Van Der Ploeg's inventive spirit and dedication to scientific advancement have not only led to impactful patents but have also enhanced our understanding of biological receptors. His contributions continue to inspire future research and innovation within the fields of molecular biology and biochemistry.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile