Leonard S Rosenberg

Title: Innovations by Leonard S. Rosenberg

Introduction

Leonard S. Rosenberg is a notable inventor based in Flemington, NJ (US). He has made significant contributions to the field of pharmaceuticals, holding two patents that focus on stable pharmaceutical compositions. His work is particularly relevant in the treatment of epilepsy and cardiac conditions.

Latest Patents

Rosenberg's latest patents include a stable pharmaceutical composition of 3-(hydroxymethyl-5,5-diphenylhydantoin disodium phosphate ester). This prodrug of 5,5-diphenylhydantoin (phenytoin) is commonly used for managing epilepsy and other convulsive states. His research indicates that controlling the pH of the composition between 8.3 to 9.4 minimizes degradation to phenytoin, thereby enhancing product stability. Another patent describes an injectable, aqueous pharmaceutical composition for treating cardiac conditions. This composition contains methyl 3-[4-(2-hydroxy-3-isopropylamino)propoxy]phenylpropionate hydrochloride (esmolol) and is designed to maintain stability in an aqueous solution, which is crucial for effective treatment.

Career Highlights

Leonard S. Rosenberg is associated with E.I. du Pont de Nemours and Company, where he has contributed to innovative pharmaceutical solutions. His work has been instrumental in developing stable compositions that improve the efficacy of existing medications.

Collaborations

Rosenberg has collaborated with notable coworkers such as Earl R. Speicher and Cheryl Black, contributing to advancements in pharmaceutical research and development.

Conclusion

Leonard S. Rosenberg's contributions to pharmaceutical innovations demonstrate his commitment to improving treatment options for patients. His patents reflect a deep understanding of chemical stability and its importance in drug formulation.