Company Filing History:
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Years Active: 1986-2002
Title: Leonard D. Kohn: Innovator in Autoimmune Disease Treatment
Introduction
Leonard D. Kohn is a prominent inventor based in Bethesda, MD, known for his contributions in the field of pharmaceuticals, particularly in methods for treating autoimmune diseases. With a total of four patents to his name, Kohn's innovative approaches have made significant strides in medical science.
Latest Patents
Among Kohn's latest inventions are several patents focused on methimazole derivatives and tautomeric cyclic thiones aimed at treating autoimmune diseases. His first patent presents methods for treating autoimmune diseases in mammals and for preventing or managing transplantation rejection. This invention introduces specifically-defined methimazole derivatives and tautomeric cyclic thione compounds, alongside pharmaceutical compositions that include those compounds. These developments demonstrate enhanced efficacy, matching or surpassing the effectiveness of methimazole while ensuring a reduced impact on thyroid function. Furthermore, these compounds exhibit greater solubility in standard pharmaceutical vehicles.
Another patent extends these discoveries by detailing methods that utilize drugs capable of suppressing the expression of MHC Class I molecules, critically important in treating autoimmune diseases and preventing transplant rejection. Kohn's work includes in vivo and in vitro assays that facilitate the identification and development of drugs targeting MHC Class I molecules, advancing the therapeutic landscape for various autoimmune conditions.
Career Highlights
Leonard D. Kohn has had a noteworthy career, contributing his expertise and innovative ideas while working with significant institutions, including the United States of America as represented by the Department of Health. His work has been instrumental in fostering advancements in pharmaceutical applications geared toward complex health issues.
Collaborations
Throughout his career, Kohn has collaborated with renowned professionals like Dinah S. Singer and Edna Mozes. These collaborations have further enriched his research pursuits and contributed to the successful development of his patents.
Conclusion
Leonard D. Kohn stands out as an influential inventor in the pharmaceutical field, with his recent patents paving the way for new treatment methodologies for autoimmune diseases. His ongoing commitment to innovation, in collaboration with esteemed colleagues, continues to inspire progress in medical science.