Lee E Goldstein

Title: Innovations of Lee E Goldstein

Introduction

Lee E Goldstein is a notable inventor based in Marblehead, MA (US), recognized for his contributions to the field of microscopy and ocular imaging. With a total of nine patents to his name, Goldstein has made significant advancements that enhance the capabilities of imaging technologies.

Latest Patents

One of Goldstein's latest inventions is the correlation confocal microscope. This innovative device utilizes correlated photon pairs to improve resolution. It features a light beam that converges on a sample, with an objective that gathers light to generate an image beam. A modulator applies a spatial pattern of modulation to the source light beam, defining spatially correlated photons. These correlations are preserved in the modulated light gathered from the sample. A modulation-selective filter function is then applied to generate a filtered light beam of like-modulated photons. Additionally, a coincidence detector identifies temporally coincident photon pairs, producing a pulse output that indicates the magnitude of a light-detectable property of the sample.

Another significant patent is related to ocular imaging. This system performs quasi-elastic light scattering and fluorescent ligand scanning on a subject's eye. It includes a light source that transmits light toward the eye, a lens that focuses the scattered light, and a measurement reflector that receives and reflects a portion of the focused light. A camera captures this light and provides an image, while a processor analyzes the intensities to determine the location of a reference point corresponding to an interface of the eye.

Career Highlights

Goldstein has worked with prestigious institutions such as Brigham and Women's Hospital and General Hospital Corporation. His work in these organizations has allowed him to develop and refine his innovative technologies, contributing to advancements in medical imaging.

Collaborations

Throughout his career, Goldstein has collaborated with notable colleagues, including Leo T Chylack, Jr. and Ashley I Bush. These partnerships have fostered a collaborative environment that has led to significant advancements in their respective fields.

Conclusion

Lee E Goldstein's contributions to microscopy and ocular imaging demonstrate his innovative spirit and dedication to advancing technology. His patents reflect a commitment to improving imaging techniques, which have the potential to enhance medical diagnostics and research.