Lawrence Shapiro

Title: Innovations of Lawrence Shapiro in HIV-1 Research

Introduction

Lawrence Shapiro is a prominent inventor based in New York, NY, known for his significant contributions to the field of HIV-1 research. With a total of three patents to his name, Shapiro has focused on developing neutralizing antibodies that target the HIV-1 virus, aiming to improve detection and treatment methods.

Latest Patents

Shapiro's latest patents include the development of 10E8 neutralizing antibody variants that bind to the MPER region of HIV-1 GP41. These patents disclose neutralizing antibodies that specifically bind to HIV-1 Env and their antigen-binding fragments. Additionally, the patents provide nucleic acids encoding these antibodies, vectors, and host cells. Methods for detecting HIV-1 using these antibodies are also outlined. Furthermore, the use of these antibodies, antigen-binding fragments, nucleic acids, and vectors to prevent and/or treat HIV-1 infections is disclosed.

Career Highlights

Throughout his career, Lawrence Shapiro has worked with esteemed organizations such as the National Institutes of Health, a component of the US Department of Health & Human Services, and Columbia University. His work in these institutions has significantly advanced the understanding and treatment of HIV-1.

Collaborations

Shapiro has collaborated with notable colleagues, including Young Do Kwon and Ivelin Georgiev, contributing to the innovative research in the field of HIV-1.

Conclusion

Lawrence Shapiro's work in developing neutralizing antibodies against HIV-1 has the potential to transform the landscape of HIV treatment and prevention. His patents and collaborations reflect a commitment to advancing medical science and improving public health outcomes.