The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Feb. 27, 2015
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
The Trustees of Columbia University IN the City of New York, New York, NY (US);
Centre for the Aids Programme of Research IN South Africa, Durban, ZA;
University of the Witwatersrand, Johannesburg, Johannesburg, ZA;
National Health Laboratory Service, Sandringham, ZA;
Chaim Aryeh Schramm, Bronx, NY (US);
Jason Gorman, Washington, DC (US);
John Mascola, Rockville, MD (US);
Lawrence Stewart Shapiro, New York, NY (US);
Lynn Morris, Randburg, ZA;
Nicole Amy Doria-Rose, Kensington, MD (US);
Penelope Linda Moore, Modderfontein, ZA;
Peter Dak Pin Kwong, Washington, DC (US);
Salim Safurdeen Abdool Karim, Durban, ZA;
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, Bethesda, MD (US);
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, New York, NY (US);
CENTRE FOR THE AIDS PROGRAMME OF RESEARCH IN SOUTH AFRICA, Durban, ZA;
UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG, Johannesburg, ZA;
NATIONAL HEALTH LABORATORY SERVICE, Sandringham, ZA;
Abstract
The present invention relates anti-HIV therapies and prophylaxis. Specifically, the invention relates to broadly neutralizing antibodies against HIV-1, nucleic acids encoding these antibodies, vectors comprising the nucleic acids and cells and pharmaceutical compositions Comprising said vectors and/or antibodies. The present invention also relates to use of the antibodies and/or vectors for the treatment and/or prevention of HIV-1 infection in a subject. Furthermore, the invention also relates to a kit containing the antibodies of the invention.