Company Filing History:
Years Active: 2002-2003
Title: The Innovative Contributions of Lawrence Restaino
Introduction
Lawrence Restaino is a notable inventor based in Chicago, IL (US). He has made significant contributions to the field of microbial detection, holding a total of 2 patents. His work focuses on developing innovative methods and compounds for identifying pathogenic bacteria.
Latest Patents
Restaino's latest patents include groundbreaking inventions such as the detection of microbial metabolites and potentially fluorogenic compounds. The invention provides compounds of formula (I), where R, R, R, R, and R are independently selected from hydrogen and chromogenic substituents, and X is selected from the group consisting of hydroxyl; OR, wherein R is selected from the group consisting of C-C alkyl; and O Me, where Me is a cation derived from an organic or inorganic base. A preferred species of formula (I) is 4-Methylumbelliferyl myo-inositol-1-phosphate and salts thereof with an organic or inorganic base. The invention also outlines fluorogenic methods for detecting various pathogenic bacteria, including Listeria, Staphylococcus, and Clostridium species, using substrates containing at least one formula (I) compound. Additionally, a kit for detecting a phosphatidyl-inositol-specific phospholipase C enzyme as an indication of bacterial activity is disclosed.
Career Highlights
Restaino is currently employed at Biosynth Ag, where he continues to innovate and contribute to the field of microbial detection. His work has garnered attention for its potential applications in public health and safety.
Collaborations
Some of his notable coworkers include Günter Schabert and Elon W. Frampton, with whom he collaborates on various research projects.
Conclusion
Lawrence Restaino's contributions to microbial detection through his innovative patents highlight his importance in the field. His work not only advances scientific knowledge but also has practical implications for health and safety.