Cambridge, MA, United States of America

Lawrence Klein

USPTO Granted Patents = 25 

 

Average Co-Inventor Count = 2.8

ph-index = 6

Forward Citations = 81(Granted Patents)


Location History:

  • Alhambra, IL (US) (1988 - 1991)
  • Cambridge, MA (US) (2020 - 2024)

Company Filing History:


Years Active: 1988-2025

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25 patents (USPTO):Explore Patents

Title: Lawrence Klein: Innovator in Gene Editing and Pain Treatment

Introduction

Lawrence Klein, based in Cambridge, MA, is a prolific inventor noted for his contributions to gene editing and pain treatment technologies. With an impressive portfolio of 22 patents, Klein is at the forefront of innovations that have the potential to revolutionize healthcare and therapeutic approaches.

Latest Patents

Klein's recent patents focus on groundbreaking compositions and methods for gene editing. His work titled "Compositions and methods for gene editing" describes materials and methodologies designed to treat patients with conditions associated with ANGPTL3, either ex vivo or in vivo. This application also outlines strategies for editing and modulating the expression of the ANGPTL3 gene in a cell through genome editing.

Additionally, he has developed "Materials and methods for treatment of pain-related disorders," which aim to address conditions associated with SCN10A. Similar to his previous work, this patent outlines techniques for editing and modulating the expression of the SCN10A gene in cells, thus paving the way for novel pain management solutions.

Career Highlights

Klein's entrepreneurial journey includes significant contributions to major companies, most notably Crispr Therapeutics AG and Vertex Pharmaceuticals, Inc. His work at these leading organizations underscores his key role in the advancement of biotechnological innovations and the development of cutting-edge therapeutics.

Collaborations

Klein has worked alongside esteemed colleagues such as Jonathan Alexander Terrett and Demetrios Kalaitzidis. These collaborations have fostered an environment of creativity and innovation, allowing for the exchange of ideas and the refinement of groundbreaking technologies.

Conclusion

Lawrence Klein's esteemed career as an inventor is marked by his commitment to tackling complex medical challenges through innovative solutions. With his extensive patent portfolio, Klein continues to make significant strides in the realms of gene editing and pain treatment, promising a brighter future for patients worldwide.

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