Lawrence J Parkhurst

Title: Innovations in DNA Detection by Lawrence J Parkhurst

Introduction

Lawrence J Parkhurst is a notable inventor based in Lincoln, NE (US). He has made significant contributions to the field of molecular biology, particularly in the detection of point mutations in DNA. With a total of 2 patents, his work has the potential to enhance genetic research and diagnostics.

Latest Patents

Parkhurst's latest patents focus on a method for detecting point mutations in DNA utilizing fluorescence energy transfer (FRET). This innovative approach involves a fluorescently labeled oligomeric probe that changes its fluorescence emission based on its interaction with DNA. The probe is labeled at both ends with fluorescence dyes that act as a donor/acceptor pair for FRET. The dramatic change in fluorescence occurs when the probe is hybridized to the complementary DNA strand and subsequently melts away, indicating the presence of a point mutation. This method allows for the quick and accurate detection of mutations, providing valuable insights into genetic variations.

Career Highlights

Lawrence J Parkhurst is affiliated with the University of Nebraska, where he continues to advance research in molecular biology. His work has garnered attention for its practical applications in genetic testing and research.

Collaborations

Parkhurst has collaborated with notable colleagues, including Kay M Parkhurst and Lyle R Middendorf, contributing to a rich environment of innovation and discovery.

Conclusion

Lawrence J Parkhurst's contributions to DNA detection through innovative methods highlight the importance of research in genetics. His patents pave the way for advancements in understanding genetic mutations and their implications.