Lawrence E Patterson

Title: Innovations by Lawrence E Patterson

Introduction

Lawrence E Patterson is a notable inventor based in Indianapolis, IN (US). He has made significant contributions to the field of chemistry, particularly in the synthesis of complex organic compounds. With a total of 3 patents to his name, Patterson's work has implications in pharmaceuticals and biochemistry.

Latest Patents

Patterson's latest patents include the synthesis of benzo[f]quinolinones and a process for preparing 2',2'-difluoronucleosides. The latter patent describes a method for producing lactone intermediates to 2',2'-difluoronucleosides, minimizing reversion back to the lactone's open chain precursor. This process allows for the selective isolation of the desired erythro enantiomer from an enantiomeric mixture of erythro and threo lactones in crystalline form. Additionally, it outlines a method for producing 2'-deoxy-2',2'-difluoronucleosides in a specific anomeric ratio, along with processes for isolating β-2'-deoxy-2',2'-difluorocytidine.

Career Highlights

Patterson is currently employed at Eli Lilly and Company, a leading pharmaceutical firm known for its innovative research and development. His work at Eli Lilly has allowed him to focus on advancing drug development through his expertise in organic synthesis.

Collaborations

Throughout his career, Patterson has collaborated with esteemed colleagues such as Perry C Heath and Ta-Sen Chou. These collaborations have contributed to the successful development of his patented processes and innovations.

Conclusion

Lawrence E Patterson's contributions to the field of chemistry and his innovative patents highlight his role as a significant inventor in the pharmaceutical industry. His work continues to influence advancements in drug development and organic synthesis.