Laurence Bonnafoux

Title: The Innovative Contributions of Laurence Bonnafoux

Introduction

Laurence Bonnafoux is a notable inventor based in Martigny, Switzerland. She has made significant strides in the field of biotechnology, particularly in the development of modified antibodies for therapeutic applications. With a total of 2 patents to her name, her work is paving the way for advancements in drug conjugation.

Latest Patents

Her latest patents focus on CL and/or CH1 mutated antibodies for drug conjugation. These antibodies have modified constant regions that allow for the conjugation of the antibody to a payload, such as a therapeutic agent. The preferred antibodies include a mutation at light chain position 180, with the most favorable mutations being to residues such as C, K, Q, or a non-natural amino acid. Additional mutations may also be combined with the mutation at position 180, including various positions on both light and heavy chains according to a positional numbering convention.

Career Highlights

Laurence is currently employed at Lonza Inc., a leading company in the life sciences sector. Her innovative work in antibody modification is contributing to the development of more effective therapeutic agents.

Collaborations

She collaborates with esteemed colleagues, including Ramon Gomez De La Cuesta and Jesús Zurdo, to further enhance her research and development efforts.

Conclusion

Laurence Bonnafoux's contributions to the field of biotechnology through her innovative patents and collaborations are noteworthy. Her work continues to influence the development of advanced therapeutic solutions.