Lauren P Blair

Title: Lauren P Blair: Innovator in Methyltransferase and Demethylase Measurements

Introduction

Lauren P Blair is a prominent inventor based in New Haven, CT (US). She has made significant contributions to the field of biochemistry, particularly in the measurement of methyltransferase and demethylase activities. Her innovative work has led to the development of methods and kits that enhance our understanding of these critical enzymatic processes.

Latest Patents

Lauren P Blair holds a patent for "Methods and kits for quantitative methyltransferase and demethylase measurements." This invention provides methods and kits for characterizing the activity of a methyltransferase or demethylase. The method involves enzymatically methylating or demethylating in vitro a substrate that is a peptide fragment of a full-length polypeptide. Subsequently, the substrate is non-enzymatically methylated with methyl groups that differ in molecular weight from the enzymatically added or removed methyl groups. Typically, deuterated or formaldehyde is used for this non-enzymatic methylation. The fully methylated substrate is then characterized by mass spectrometry to determine the ratio of enzymatically produced nonmethyl, monomethyl, and dimethyl residues on the peptide. This patent highlights her innovative approach to biochemical measurement.

Career Highlights

Lauren P Blair is affiliated with the University of Arkansas, where she continues her research and development in the field of biochemistry. Her work has garnered attention for its potential applications in various scientific and medical fields. With a focus on advancing our understanding of enzymatic activities, she has established herself as a key figure in her area of expertise.

Collaborations

Throughout her career, Lauren has collaborated with notable colleagues, including Alan J Tackett and Nathan L Avaritt. These collaborations have further enriched her research and contributed to the advancement of knowledge in her field.

Conclusion

Lauren P Blair is a distinguished inventor whose work in methyltransferase and demethylase measurements has made a significant impact in biochemistry. Her innovative methods and dedication to research continue to inspire advancements in the scientific community.