This inventor holds 4 USPTO granted patents and 2 published patent applications. Top assignee: St. Jude Children's Research Hospital. Active years: 2014-2019.
Company Filing History:
Years Active: 2014-2019
Title: The Innovative Contributions of Lauren Collison
Introduction
Lauren Collison is a prominent inventor based in Memphis, TN (US). She has made significant contributions to the field of immunology, particularly through her work on Interleukin 35 (IL-35) and its receptor. With a total of 4 patents to her name, Collison's research has the potential to impact therapeutic approaches in various medical conditions.
Latest Patents
One of her latest patents involves the development of a polynucleotide encoding the IL-35 receptor. This receptor comprises a heterodimeric complex of the Interleukin 12Rβ2 receptor and the gp130 receptor. The patent outlines various compositions that include the IL-35R complex, along with polynucleotides encoding the same. It also details methods for modulating the activity of IL-35R and effector T cell functions using IL-35R antagonists and agonists. Additionally, she has developed methods for screening IL-35R binding agents and modulating agents, as well as various treatment methods. Another significant patent focuses on monoclonal antibodies to interleukin 35, providing methods for regulating T cell function, particularly regulatory T cell activity. This invention includes administering a therapeutically effective amount of an IL-35-specific binding agent to enhance the immunogenicity of vaccines, including cancer vaccines.
Career Highlights
Lauren Collison is affiliated with St. Jude Children's Research Hospital, where she conducts her groundbreaking research. Her work is instrumental in advancing our understanding of immune responses and developing new therapeutic strategies.
Collaborations
Collison collaborates with notable colleagues, including Dario A. Vignali and Kate Vignali, who contribute to her research endeavors.
Conclusion
Lauren Collison's innovative work in the field of immunology, particularly regarding IL-35 and its receptor, showcases her dedication to advancing medical science. Her patents reflect her commitment to developing new therapeutic methods that could significantly benefit patients.