Laura Wingler

Title: Laura Wingler: Innovator in G-Protein Coupled Receptor Research

Introduction

Laura Wingler is a prominent inventor based in Durham, NC (US). She has made significant contributions to the field of biochemistry, particularly in the study of G-protein coupled receptors (GPCRs). Her innovative work has led to advancements in understanding receptor modulation, which has important implications for treating various medical conditions.

Latest Patents

Laura Wingler holds a patent titled "System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators." This patent focuses on a G-protein coupled receptor complex that includes a chimeric GPCR with a non-native amino acid sequence and a synthetic phosphopeptide. The invention also describes an in vitro method for producing this complex and identifying compounds that can modulate its activity. The positive allosteric modulators identified through this research have potential applications in treating obstructive airway diseases, bronchospasm, and pre-term labor.

Career Highlights

Laura is affiliated with Duke University, where she continues her research and development in the field of GPCRs. Her work has not only contributed to academic knowledge but also has practical applications in pharmacology and therapeutic interventions.

Collaborations

Laura has collaborated with notable researchers such as Robert J. Lefkowitz and Seungkirl Ahn. These collaborations have further enriched her research and expanded the impact of her work in the scientific community.

Conclusion

Laura Wingler is a trailblazer in the field of G-protein coupled receptor research, with her innovative patent paving the way for new therapeutic strategies. Her contributions to science exemplify the importance of innovation in addressing complex medical challenges.