Cambridge, MA, United States of America

Laura T Kliman



Average Co-Inventor Count = 13.0

ph-index = 2

Forward Citations = 41(Granted Patents)


Company Filing History:


Years Active: 2009-2010

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2 patents (USPTO):Explore Patents

Title: Laura T Kliman: Innovator in Spirocyclic Compounds

Introduction

Laura T Kliman is a notable inventor based in Cambridge, MA (US). She has made significant contributions to the field of medicinal chemistry, particularly through her work on spirocyclic compounds. With a total of 2 patents, her innovations are paving the way for advancements in cancer treatment and other medical applications.

Latest Patents

Kliman's latest patents focus on a novel class of substituted spirocyclic compounds. These compounds have the ability to inhibit histone deacetylase, making them suitable for selectively inducing terminal differentiation and arresting cell growth or apoptosis of neoplastic cells. This inhibition is crucial for treating patients with tumors characterized by the proliferation of neoplastic cells. Additionally, her compounds may be beneficial in preventing and treating TRX-mediated diseases, including autoimmune, allergic, and inflammatory diseases, as well as neurodegenerative diseases affecting the central nervous system. The patents also detail pharmaceutical compositions that incorporate these compounds, ensuring safe dosing regimens that yield therapeutically effective amounts in vivo.

Career Highlights

Throughout her career, Laura T Kliman has worked with prominent companies such as Merck & Company, Inc. and Merck Sharp & Dohme Corporation. Her experience in these organizations has contributed to her expertise in drug development and innovation in the pharmaceutical industry.

Collaborations

Kliman has collaborated with notable professionals in her field, including Scott C Berk and Joshua Close. These partnerships have likely enhanced her research and development efforts, leading to her successful patent applications.

Conclusion

Laura T Kliman is a distinguished inventor whose work on spirocyclic compounds holds promise for significant advancements in medical treatments. Her contributions to the field are invaluable, and her patents reflect her commitment to innovation in healthcare.

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