Laura Jane Mariano

Title: Laura Jane Mariano: Innovator in Magnetic Resonance Spectroscopy

Introduction

Laura Jane Mariano is a distinguished inventor based in Somerville, MA (US). She has made significant contributions to the field of medical diagnostics, particularly in the areas of post-traumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI). With a total of 6 patents, her work has the potential to transform how these conditions are diagnosed and treated.

Latest Patents

One of her latest patents is a method and system for diagnosing PTSD and mTBI using magnetic resonance spectroscopy (MRS). This innovative diagnostic system utilizes MRS signals collected in vivo from specific regions of the brain. By applying wavelet decomposition to these signals, the amplitude of the wavelet coefficients and their location are used as features for training diagnostic classifiers. These classifiers are developed through the analysis of features from individuals with known health statuses, allowing for accurate diagnosis of patients based on wavelet features extracted from their MRS scans.

Another notable patent involves a method and procedure for signal estimation and data harmonization for MRS. This system analyzes raw MRS data from multiple scanners, ensuring consistency in the resulting MRS signals. The harmonized data is crucial for analysis by radiologists and other physicians, enhancing the reliability of diagnostic results.

Career Highlights

Laura has worked with prestigious organizations such as the Charles Stark Draper Laboratory, Inc. and Brigham and Women's Hospital, Inc. Her experience in these institutions has allowed her to collaborate with leading experts in the field, further advancing her research and innovations.

Collaborations

Some of her notable coworkers include John M Irvine and Nirmal Keshava. Their collaborative efforts have contributed to the success of her projects and the development of groundbreaking technologies in medical diagnostics.

Conclusion

Laura Jane Mariano is a pioneering inventor whose work in magnetic resonance spectroscopy is paving the way for improved diagnostic methods for PTSD and mTBI. Her innovative patents and collaborations highlight her commitment to advancing medical technology and improving patient outcomes.