This inventor holds 3 USPTO granted patents. Top assignees: Amylogene Hb, Rhone-Poulenc Rorer Pharmaceuticals Inc., Rhone-Poulenc Rorer S.a.. Active years: 2001.
Company Filing History:
Years Active: 2001
Title: Innovations of Lars Rask in Calcium Sensor Protein Research
Introduction
Lars Rask is a notable inventor based in Uppsala, Sweden. He has made significant contributions to the field of biochemistry, particularly in the study of calcium sensor proteins. With a total of 3 patents, his work has implications for understanding calcium regulation in various organ systems.
Latest Patents
Rask's latest patents focus on nucleic acids encoding human calcium sensor proteins. One of his key inventions involves the isolation of a cDNA clone that encodes the calcium sensor found in human placenta. Subsequent Northern blots have confirmed mRNA expression in human parathyroid and kidney tubule cells. His research demonstrates close sequence similarity with the rat Heymann nephritis antigen, a glycoprotein known for its calcium binding ability. Immunohistochemistry has substantiated a tissue distribution of the calcium sensor protein that is similar to the previously described Heymann antigen. Rask proposes that this identified calcium sensor protein serves as a universal sensor for recognizing variations in extracellular calcium, playing a crucial role in calcium regulation across different organ systems. The calcium sensor protein belongs to the LDL-superfamily of glycoproteins, which are primarily known to function as protein receptors while also possessing important calcium binding capabilities.
Career Highlights
Throughout his career, Lars Rask has worked with several prominent companies, including Amylogene and Rhône-Poulenc Rorer Pharmaceuticals Inc. His experience in these organizations has contributed to his expertise in the field of biochemistry and patent development.
Collaborations
Rask has collaborated with notable colleagues such as Göran Akerström and Claes Juhlin. These partnerships have likely enhanced his research and innovation efforts in the realm of calcium sensor proteins.
Conclusion
Lars Rask's contributions to the understanding of calcium sensor proteins are significant and impactful. His patents reflect a deep commitment to advancing knowledge in biochemistry and its applications in health and medicine.