Company Filing History:
Years Active: 1978
Title: Lars-Olof Edvard Lindquist: Innovator in Albumin Isolation
Introduction
Lars-Olof Edvard Lindquist is a notable inventor based in Uppsala, Sweden. He has made significant contributions to the field of biochemistry, particularly in the isolation of albumin from blood products. His innovative methods have the potential to enhance the efficiency and purity of albumin extraction, which is crucial for various medical applications.
Latest Patents
Lindquist holds a patent for a method of isolating albumin from blood products. This invention relates to a new method of isolating highly purified albumin in high yields from plasma products. According to the invention, a particular plasma fraction, containing albumin in dissolved form and being essentially free from the coagulation factors I, II, VII, VIII, IX, and X, as well as from the main part of IgG, is subjected to a two-step chromatographic separation using aqueous buffer systems. The first step is carried out on an anion exchanger, and the second step on a cation exchanger, or vice versa. In a preferred embodiment, a buffer of pH 4.5 - 4.9 and an ionic strength of 0.025 - 0.1 is used for the separation on the anion exchanger, whereas a buffer of pH 5.2 - 6.5 and an ionic strength of 0.1 - 0.05 is used for the separation on the cation exchanger.
Career Highlights
Lindquist has worked at Pharmacia Fine Chemicals AB, where he has been able to apply his expertise in biochemistry and patent his innovative methods. His work has contributed to advancements in the pharmaceutical industry, particularly in the production of blood-derived products.
Collaborations
Throughout his career, Lindquist has collaborated with notable colleagues such as Jan Hakan Berglof and John Malcolm Curling. These collaborations have likely enriched his research and contributed to the development of his patented methods.
Conclusion
Lars-Olof Edvard Lindquist is a distinguished inventor whose work in isolating albumin from blood products has significant implications for the medical field. His innovative methods and collaborations highlight his contributions to biochemistry and the pharmaceutical industry.