Larry U Tan

Title: Larry U Tan: Innovator in Pertussis Vaccine Development

Introduction

Larry U Tan is a notable inventor based in Mississauga, Canada. He has made significant contributions to the field of vaccine development, particularly in the area of pertussis vaccines. With a total of 7 patents to his name, Tan's work has had a lasting impact on public health.

Latest Patents

One of his latest patents focuses on the purification of a pertussis outer membrane protein known as Pertactin. This protein is recovered in a stable biologically pure form, free from detectable adenylate cyclase activity. The process involves the selective removal of pertussis toxin and filamentous haemagglutinin from fermentation broth, followed by ammonium sulfate precipitation and various chromatographic techniques. Another significant patent involves the preparation of acellular pertussis vaccines. This process includes the extraction of fimbrial agglutinogens from Bordetella strains, which can be combined with other pertussis antigens to create effective vaccines.

Career Highlights

Throughout his career, Larry U Tan has worked with reputable organizations, including Connaught Laboratories Limited. His expertise in vaccine development has positioned him as a key figure in the field, contributing to advancements that enhance vaccine efficacy and safety.

Collaborations

Tan has collaborated with several professionals in his field, including Gail E Jackson and Raafat Emil Fahim. These collaborations have further enriched his research and development efforts.

Conclusion

Larry U Tan's innovative work in the development of pertussis vaccines showcases his dedication to improving public health through scientific advancements. His contributions continue to influence the field of immunology and vaccine research.