Company Filing History:
Years Active: 2007
Title: Innovations by Larry Eden in Stabilizing 5-Azacytidine
Introduction
Larry Eden is an accomplished inventor based in Overland Park, KS (US). He has made significant contributions to the field of pharmaceuticals, particularly in the stabilization of 5-azacytidine. His innovative methods have the potential to enhance the storage and determination of this important compound.
Latest Patents
Larry Eden holds a patent for "Methods for stabilizing 5-azacytidine in plasma." This invention provides methods for stabilizing 5-azacytidine against hydrolysis in plasma. By extracting the 5-azacytidine into acetonitrile and zinc sulfate, the compound can be stored for at least about 3 hours at room temperature and for at least about 4 days at about -70°C. If the acetonitrile is removed and evaporated to dryness, the 5-azacytidine in the resulting residue remains stable for at least about 14 months at -70°C. The invention also includes methods for determining the 5-azacytidine in acetonitrile or in the acetonitrile residue, utilizing techniques such as high-performance liquid chromatography. This patent highlights his innovative approach to improving the handling of 5-azacytidine.
Career Highlights
Larry Eden is associated with Pharmion Corporation, where he has contributed to advancements in pharmaceutical technologies. His work has focused on enhancing the stability and usability of critical compounds in medical applications. With a patent count of 1 patent, his contributions are noteworthy in the field.
Collaborations
Larry has collaborated with notable colleagues, including Marsha Luna and Steven Burmaster. Their combined expertise has likely contributed to the success of their projects and innovations.
Conclusion
Larry Eden's work in stabilizing 5-azacytidine represents a significant advancement in pharmaceutical science. His innovative methods not only improve the storage of this compound but also facilitate its determination in laboratory settings. His contributions continue to impact the field positively.