Larry Bartelt

Title: Innovations of Larry Bartelt in Pharmaceutical Manufacturing

Introduction

Larry Bartelt is an accomplished inventor based in Highland Park, IL (US). He has made significant contributions to the field of pharmaceutical manufacturing, particularly in the development of crystalline forms of rapamycin analogs. With a total of 4 patents to his name, Bartelt's work has had a notable impact on the industry.

Latest Patents

One of Bartelt's latest patents focuses on methods of manufacturing crystalline forms of rapamycin analogs. This innovative process involves combining the rapamycin analog with an organic medium to create a mixture. The mixture is then incubated until the rapamycin analog crystallizes, allowing for the recovery of the crystalline form. The organic medium can serve as a solvent, and the process may include steps such as dissolving the rapamycin analog into the solvent and stirring the mixture until crystallization occurs. Additionally, the process can involve forming a slurry of crystalline rapamycin analog and creating a biphasic mixture by combining an antisolvent with the rapamycin analog and the solvent.

Another significant patent by Bartelt provides a rapamycin analog composition that includes a crystalline form of the rapamycin analog. This crystalline form can be a hydrate, dehydrate, solvate, or desolvate. The rapamycin analog may also have a structure that is optionally a prodrug, salt, derivative, or combination thereof.

Career Highlights

Larry Bartelt has built a successful career at Abbott Laboratories Corporation, where he has been instrumental in advancing pharmaceutical technologies. His expertise in the field has led to the development of innovative processes that enhance the manufacturing of important pharmaceutical compounds.

Collaborations

Throughout his career, Bartelt has collaborated with notable colleagues, including Shekhar Viswanath and Robert M. Leanna. These partnerships have contributed to the success of his projects and the advancement of pharmaceutical research.

Conclusion

Larry Bartelt's contributions to the field of pharmaceutical manufacturing, particularly through his innovative patents, have made a significant impact on the industry. His work continues to influence the development of effective pharmaceutical solutions.