Laichuang Han

Title: Laichuang Han: Innovator in Gene Engineering

Introduction

Laichuang Han is a prominent inventor based in Wuxi, China. He has made significant contributions to the field of gene engineering, holding a total of 2 patents. His work focuses on developing efficient methods for gene expression and synthetic biology.

Latest Patents

Han's latest patents include a method for constructing efficient promoters and an efficiently-induced expression system based on an artificial series promoter. The first patent discloses a method that connects natural promoters identified by different sigma subunits in series. This innovative approach optimizes the lengths of intervening sequences to enhance promoter activity. The method allows for the design of promoters with higher activity and compatibility, making it applicable in constructing exogenous protein expression systems.

The second patent presents an efficiently-induced expression system that utilizes an artificial series constitutive promoter. This system regulates the activity of the promoter through an inducer, achieving an activity level approximately 15 times higher than that of a strongly constitutive promoter. The simplicity and high activity of this expression system highlight its potential in heterologous protein expression and synthetic biology research.

Career Highlights

Laichuang Han is affiliated with Jiangnan University, where he continues to advance research in gene engineering. His innovative approaches have garnered attention in the scientific community, contributing to the development of efficient gene expression systems.

Collaborations

Han collaborates with notable colleagues, including Zhemin Zhou and Wenjing Cui, to further enhance research outcomes in their field.

Conclusion

Laichuang Han's contributions to gene engineering through his innovative patents demonstrate his commitment to advancing scientific research. His work has significant implications for the future of synthetic biology and protein expression systems.