Kuo-Sen Huang

Title: **Innovator Spotlight: Kuo-Sen Huang**

Introduction

Kuo-Sen Huang, an accomplished inventor based in Livingston, NJ, has significantly contributed to the field of biomedical innovation. With three patents to his name, his work focuses on methods that enhance our understanding of complex biological interactions, particularly those associated with growth factors and heparanase activity.

Latest Patents

Huang's latest patents showcase innovative methodologies aimed at testing the abilities of various agents in biological processes. His first patent presents a method for testing an agent’s capacity to inhibit fibroblast growth factor (FGF) binding with labeled heparan sulfate. This method entails interacting immobilized FGF on a solid support with an agent and labeled heparan sulfate, followed by detecting the presence of a label in the solution, providing insight into the biological interactions involved.

Additionally, Huang has developed a method for screening agents that inhibit heparanase activity. This process involves interacting immobilized heparanase substrate binding proteins with labeled substrates and assessing the ability of various agents to interfere with heparanase activity, further enhancing research into therapeutic applications.

Moreover, he addresses the inhibition of binding between FGF and heparanase substrates using a similar methodology, underscoring his commitment to advancing knowledge in this critical area of research.

Career Highlights

Kuo-Sen Huang is currently associated with Hoffmann-La Roche Inc., a company renowned for its contributions to pharmaceuticals and diagnostics. His role within this prestigious organization allows him to collaborate closely with experts and drive innovations in drug discovery and development.

Collaborations

Throughout his career, Huang has worked alongside notable colleagues, including Anthony Neri and John Lawson Roberts. These collaborations have fostered an environment of innovation and have enabled the advancement of numerous projects that leverage their combined expertise in the field.

Conclusion

Kuo-Sen Huang exemplifies the spirit of innovation, with his patented methods poised to enhance our understanding of important biological processes. His ongoing work at Hoffmann-La Roche Inc. continues to break new ground, highlighting the impact of inventors in the field of biomedical research and the potential for future discoveries.