Company Filing History:
Years Active: 2024
Title: Kun Duan: Innovator in T Cell Receptor Technology
Introduction
Kun Duan is a notable inventor based in Shenzhen, China. He has made significant contributions to the field of immunology through his innovative work on T cell receptors. His research focuses on enhancing the recognition of specific epitopes, which is crucial for effective drug development.
Latest Patents
Kun Duan holds a patent for the MART-1 (27-35) epitope-specific T cell receptor. This invention comprises an α chain and a β chain, with the α chain containing three complementary determining regions. The specific sequences of these regions are found in positions 61-66, 84-89, and 124-136 of SEQ ID No. 3. The β chain also includes three complementary determining regions, with amino acid sequences located at positions 46-50, 68-73, and 112-125 of SEQ ID No. 4. A T cell expressing this TCR can effectively recognize a MART-1 (27-35) epitope polypeptide supported on a T2 cell and secrete IFN-γ, demonstrating the receptor's functionality. This TCR can be utilized with relevant drug targets, facilitating effective drug development.
Career Highlights
Kun Duan is currently employed at BGI Shenzhen, where he continues to advance his research in T cell receptor technology. His work is pivotal in the ongoing efforts to improve immunotherapeutic strategies.
Collaborations
Kun collaborates with esteemed colleagues, including Fei Wang and Chengchi Chao, who contribute to his research endeavors.
Conclusion
Kun Duan's innovative work in T cell receptor technology exemplifies the potential for advancements in immunotherapy. His contributions are vital for the future of drug development and therapeutic applications.