Kristina N Sigmon

Title: Innovations by Kristina N Sigmon

Introduction

Kristina N Sigmon is a notable inventor based in Durham, NC (US). She has made significant contributions to the field of medical diagnostics, particularly in assessing reperfusion after thrombolytic therapy. With a total of 2 patents, her work has the potential to improve patient outcomes in myocardial infarction cases.

Latest Patents

One of her latest patents is a method of diagnosing the presence of a persistent occlusion in a myocardial infarct patient undergoing thrombolytic therapy. This method involves detecting a series of five variables from the patient to generate the probability of a persistent occlusion. The first variable is a serum creatine kinase MB (CK-MB) level at the onset of thrombolytic therapy. The second variable is a second CK-MB level at a predetermined time after the onset of therapy. The third variable is the presence or absence of chest pain after the onset of therapy. The fourth variable is the serum myoglobin level at a predetermined time after therapy begins. In a preferred embodiment, these variables are detected within 30 minutes of each other and within about 1 to 3 hours after the initial variable is detected. An alternate embodiment includes a fifth variable reflecting the time from the onset of chest pain to the beginning of thrombolytic therapy.

Another patent by Kristina N Sigmon also focuses on a method of assessing reperfusion after thrombolytic therapy. This method similarly involves detecting three key variables: the initial CK-MB level, a second CK-MB level at a predetermined time, and the presence or absence of chest pain. The second and third variables are also detected within 30 minutes of each other and within about 1 to 3 hours after the initial variable.

Career Highlights

Kristina N Sigmon is affiliated with Duke University, where she continues her research and innovation in medical diagnostics. Her work is crucial in enhancing the understanding and treatment of myocardial infarction.

Collaborations

She has collaborated with notable professionals in her field, including Robert H Christenson and Robert M Califf. These collaborations have likely contributed to the advancement of her research and the development of her patents.

Conclusion

Kristina N Sigmon's contributions to medical diagnostics through her innovative patents demonstrate her commitment to improving patient care. Her work in assessing reperfusion after thrombolytic therapy