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Years Active: 2012-2013
Title: Kristen Viola: Innovator in Alzheimer's Disease Research
Introduction
Kristen Viola is a prominent inventor based in Chicago, IL (US). She has made significant contributions to the field of Alzheimer's disease research through her innovative work on antibodies that target specific conformations of Aβ-derived diffusible ligands, known as ADDLs. With a total of 2 patents, her inventions hold promise for advancing diagnostic and therapeutic methods for Alzheimer's disease.
Latest Patents
Kristen Viola's latest patents include the development of Anti-ADDL antibodies and their uses. These antibodies are designed to differentially recognize multi-dimensional conformations of ADDLs. They can distinguish between Alzheimer's disease and control human brain extracts, making them useful in methods for detecting ADDLs and diagnosing Alzheimer's disease. Furthermore, these antibodies block the binding of ADDLs to neurons, inhibit the assembly of ADDLs, and prevent tau phosphorylation. As a result, they are valuable in methods for preventing and treating diseases associated with soluble oligomers of amyloid β 1-42.
Career Highlights
Throughout her career, Kristen has worked with esteemed organizations such as Northwestern University and Merck Sharp & Dohme Corp. Her research has focused on the intersection of immunology and neurodegenerative diseases, leading to groundbreaking advancements in the understanding and treatment of Alzheimer's disease.
Collaborations
Kristen has collaborated with notable colleagues, including Paul Acton and Zhiqiang An. These partnerships have further enriched her research and contributed to the development of her innovative patents.
Conclusion
Kristen Viola's work exemplifies the impact of innovation in the field of Alzheimer's disease research. Her patents and collaborations highlight her commitment to advancing medical science and improving the lives of those affected by neurodegenerative diseases.