Company Filing History:
Years Active: 2016
Title: Innovations of Krishnan K Palaniappan
Introduction
Krishnan K Palaniappan is a notable inventor based in Columbia, MO (US). He has made significant contributions to the field of mass spectrometry, particularly in the detection of low abundance proteins.
Latest Patents
Palaniappan holds a patent titled "Isotopic recoding for targeted tandem mass spectrometry." This patent includes methods for detecting low abundance proteins and identifying sites of N-glycosylation on proteins. The methods involve contacting a eukaryotic cell with an isotopic labeling composition. Isotopically labeled N-glycosylated peptides obtained from the eukaryotic cell are then assessed using liquid chromatography-tandem mass spectrometry. A predetermined isotopic pattern in the mass spectrum is identified, allowing for the determination of amino acid sequences of the peptides containing that pattern.
Career Highlights
Palaniappan is affiliated with the University of California, where he continues to advance research in his field. His work has implications for various applications in biochemistry and molecular biology.
Collaborations
He has collaborated with notable scientists such as Carolyn Ruth Bertozzi and Brian Phillip Smart, contributing to the advancement of research in mass spectrometry and protein analysis.
Conclusion
Krishnan K Palaniappan's innovative work in isotopic recoding and mass spectrometry showcases his expertise and dedication to advancing scientific knowledge. His contributions are valuable to the fields of biochemistry and molecular biology.