Location History:
- Suita, JP (2010)
- Osaka, JP (2021)
Company Filing History:
1 out of 9 
1 out of 987 
1 out of 7 Years Active: 2010-2021
Title: Kotaro Saga: Innovator in Tissue Regeneration and Viral Research
Introduction
Kotaro Saga is a prominent inventor based in Suita, Japan. He has made significant contributions to the fields of tissue regeneration and viral research. With a total of 2 patents, his work focuses on innovative methods to promote healing and develop modified viruses for therapeutic applications.
Latest Patents
One of his latest patents is titled "Agents for promoting tissue regeneration by recruiting bone marrow mesenchymal stem cells and/or pluripotent stem cells into blood." This invention reveals that the intravenous administration of HMGB-1 and S100A8 can promote the healing of skin ulcers by recruiting bone marrow-derived cells to the affected area. Additionally, in a cerebral infarction model, the administration of HMGB-1 resulted in a marked reduction of cerebral infarction and an increased survival rate in treated mice.
Another significant patent is "Mutant paramyxovirus and method for production thereof." This invention provides a modified paramyxovirus with a reduced amount of receptor-binding protein compared to the wild type. The method involves introducing a nucleic acid that suppresses the expression of this protein into an animal cell, followed by infection with the paramyxovirus and isolation of the replicated virus particles. This research also includes the development of a chimera protein that can target specific cell surface markers.
Career Highlights
Kotaro Saga has worked with notable organizations such as Stemrim Inc. and Osaka University. His experience in these institutions has allowed him to advance his research and contribute to the scientific community significantly.
Collaborations
He has collaborated with esteemed colleagues, including Katsuto Tamai and Yasufumi Kaneda. Their joint efforts have furthered the understanding and application of his innovative research.
Conclusion
Kotaro Saga's work in tissue regeneration and viral research exemplifies the impact of innovative thinking in medicine. His patents reflect a commitment to advancing healthcare through scientific discovery and collaboration.