Location History:
- Bar Harbor, ME (US) (1998)
- Rockville, MD (US) (2000)
Company Filing History:
2 out of 5 
2 out of 91 
1 out of 40 Years Active: 1998-2000
Title: Konrad Noben-Trauth: Innovator in Neurosensory Genetics
Introduction
Konrad Noben-Trauth is a distinguished inventor based in Bar Harbor, ME (US). He has made significant contributions to the field of genetics, particularly in understanding neurosensory defects and obesity-related genes. With a total of 3 patents, his work has implications for both therapeutic and diagnostic applications.
Latest Patents
One of his latest patents focuses on a gene family associated with neurosensory defects. This patent provides nucleic acid compositions that encode a family of mammalian proteins expressed in the retina and brain. Members of this gene family are genetically linked to various neurosensory defects, including cochlear degeneration and cone-rod retinal dystrophy. The compositions are useful for identifying DNA sequences encoding homologous proteins and studying associated physiological pathways. Additionally, modulation of gene activity in vivo is proposed for therapeutic purposes, such as treating neurosensory defects and identifying retinal cells based on expression.
Another significant patent addresses obesity-associated genes. This patent identifies the gene responsible for the autosomal recessive mouse obesity mutation known as tub. The homologous human gene is also provided, which can be used to produce tubby protein and screen for compositions that modulate its expression. The mutation responsible for the tub phenotype is a G to T transversion that results in a larger transcript containing an unspliced intron.
Career Highlights
Throughout his career, Konrad has worked with notable organizations such as Sequana Therapeutics, Inc. and The Jackson Laboratory. His research has contributed to advancements in genetic understanding and potential treatments for various conditions.
Collaborations
Konrad has collaborated with esteemed colleagues, including Michael North and Patsy M. Nishina, further enhancing the impact of his research in the field of genetics.
Conclusion
Konrad Noben-Trauth's innovative work in genetics has paved the way for new insights into neurosensory defects and obesity. His patents reflect a commitment to advancing medical science and improving diagnostic capabilities.