Company Filing History:
Years Active: 1981-1983
Title: Komei Ohashi: Innovator in Immunoglobulin Production
Introduction
Komei Ohashi, a notable inventor based in Kumamoto, Japan, has made significant contributions to the field of immunology through his innovative methods of producing immunoglobulin. With two patents to his name, his work focuses on enhancing the efficacy and safety of immunoglobulin-based therapies.
Latest Patents
Ohashi's latest patents highlight his pioneering approaches. The first patent, titled "Method of the production of immunoglobulin having high content of monomer," presents a novel fractionation method that employs a water-soluble, basic nitrogen-containing organic compound to inhibit the by-production of undesirable aggregated molecules. This method results in immunoglobulin with a high monomer content and minimal aggregation, making it suitable for immune prophylaxis and immunotherapy without side effects.
The second patent, "Purification of gammaglobulin derivative," outlines a process for producing a highly purified S-sulfonated gammaglobulin. This process involves treating an S-sulfonated gammaglobulin with an ion exchanger in a buffer solution, allowing for the selective absorption and elution of single molecular S-sulfonated gammaglobulin. The resulting product boasts low anticomplementary activity, demonstrating excellent stability, which is advantageous for industrial applications.
Career Highlights
Ohashi is associated with the Juridical Foundation for the Chemo-sero-therapeutic Research Institute, where his research and inventions contribute to advancements in immunotherapy. His innovative methods not only enhance the therapeutic potential of immunoglobulin but also aim to improve patient safety and treatment outcomes.
Collaborations
Throughout his career, Ohashi has collaborated with esteemed colleagues, including Akinobu Funatsu and Tetsuro Sato. Their collective expertise fosters an environment of innovation, driving forward the development of new therapeutic technologies in the field of immunology.
Conclusion
Komei Ohashi stands out as a leading inventor in the production of immunoglobulin, significantly impacting the field of immunotherapy. His patents reflect a commitment to improving medical treatments for better patient outcomes, showcasing the potential of innovation in science and medicine.