Company Filing History:
Years Active: 2001-2009
Title: Koji Toyomura: Innovator in Transgenic Mammals
Introduction
Koji Toyomura is a prominent inventor based in Tsukuba, Japan. He has made significant contributions to the field of biotechnology, particularly in the development of transgenic mammals. With a total of 4 patents, his work focuses on enhancing organ transplantation through innovative genetic modifications.
Latest Patents
One of Toyomura's latest patents involves the creation of transgenic mammals that carry a transgene comprising regulatory genes capable of functioning in hyperacute rejection-occurring local cells. This invention includes a gene encoding human N-acetylglucosaminyltransferase III (GnT-III) and aims to reduce the presence of α-Gal antigens, thereby effectively inhibiting hyperacute rejection in discordant xenotransplantation. This advancement provides a promising solution for organ transplantation. Another notable patent is for transgenic non-human mammals expressing the human complement inhibitor (DAF/CD55). This invention allows for the expression of the human complement inhibitor in various organs and tissues, particularly in endothelial cells. These transgenic mammals serve as valuable laboratory animals and potential sources for organ and tissue transplantation.
Career Highlights
Koji Toyomura is currently associated with Nippon Meat Packers, Inc., where he continues to innovate in the field of genetic engineering. His work has garnered attention for its potential applications in medical treatments and organ transplantation.
Collaborations
Toyomura collaborates with notable colleagues such as Hiroshi Murakami and Tamotsu Shigehisa, contributing to a dynamic research environment that fosters innovation.
Conclusion
Koji Toyomura's contributions to the field of transgenic mammals represent a significant advancement in biotechnology. His innovative patents have the potential to revolutionize organ transplantation and improve medical treatments.