Company Filing History:
Years Active: 1996-2008
Title: Innovations of Klim King in G Protein-Coupled Receptors
Introduction
Klim King is a notable inventor based in Durham, NC (US), recognized for his contributions to the field of molecular biology. He holds a total of five patents, showcasing his innovative approach to scientific research and development. His work primarily focuses on the expression of G protein-coupled receptors in yeast, which has significant implications for drug discovery and therapeutic applications.
Latest Patents
One of Klim King's latest patents involves the expression of G protein-coupled receptors in yeast. This patent discloses a transformed yeast cell that contains a first heterologous DNA sequence coding for a mammalian G protein-coupled receptor and a second heterologous DNA sequence coding for a mammalian G protein α subunit. The yeast cell is designed to express these sequences while being incapable of expressing an endogenous G protein α-subunit. This innovative approach allows for the screening of compounds that affect the rate of dissociation of G proteins within the cell. Additionally, the patent introduces a novel DNA expression vector that facilitates the creation of these specialized yeast cells.
Career Highlights
Klim King has made significant strides in his career, particularly through his work at Duke University. His research has contributed to a deeper understanding of G protein-coupled receptors, which are crucial for various physiological processes and are a major target for drug development. His innovative methodologies and findings have positioned him as a key figure in the field of molecular biology.
Collaborations
Klim King has collaborated with esteemed colleagues such as Marc G. Caron and Robert J. Lefkowitz. These collaborations have further enhanced the impact of his research and have contributed to advancements in the understanding of G protein-coupled receptors.
Conclusion
Klim King's innovative work in the field of G protein-coupled receptors has led to significant advancements in molecular biology and drug discovery. His contributions continue to influence research and development in this critical area of science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.