Klaus Rajewsky

Title: Klaus Rajewsky: Innovator in Monoclonal Antibodies

Introduction

Klaus Rajewsky is a prominent inventor based in Cologne, Germany. He is known for his significant contributions to the field of immunology, particularly in the development of novel methods for producing autologous monoclonal antibodies.

Latest Patents

Rajewsky holds a patent titled "Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof." This invention provides innovative methods for obtaining autologous monoclonal antibodies (AMABs) to self-antigens or homologs thereof. The method involves using a genetically engineered host animal that does not biosynthesize at least one epitope of the antigen. This approach leverages the lack of self-tolerance of the host to produce antibodies specific to the antigen. The invention also encompasses the AMABs produced by these methods, as well as methods for isolating cells that utilize such AMABs with specificity for a cell surface antigen. Rajewsky has 1 patent to his name.

Career Highlights

Klaus Rajewsky is associated with Miltenyi Biotec GmbH, where he continues to advance research in the field of biotechnology. His work has had a significant impact on the development of therapeutic antibodies, which are crucial in treating various diseases.

Collaborations

Rajewsky has collaborated with notable colleagues, including Werner Mueller and Juergen Roes. These partnerships have further enhanced his research and contributions to the field.

Conclusion

Klaus Rajewsky's innovative work in the development of monoclonal antibodies showcases his expertise and dedication to advancing medical science. His contributions are vital for future therapeutic applications and research in immunology.