Kiyoshige Yoshida

Title: Kiyoshige Yoshida: Innovator in Pharmaceutical Chemistry

Introduction

Kiyoshige Yoshida is a notable inventor based in Mino, Japan. He has made significant contributions to the field of pharmaceutical chemistry, particularly through his innovative work on occlusion compounds.

Latest Patents

Yoshida holds a patent for an occlusion compound of 2-nitroxymethyl-6-chloropyridine with β-cyclodextrin. This invention addresses the volatility issues associated with 2-nitroxymethyl-6-chloropyridine in pharmaceutical preparations. The occlusion compound has a molar ratio of 2-nitroxymethyl-6-chloropyridine to β-cyclodextrin ranging from about 1:1 to about 3:1. The process for preparing this compound involves reacting 2-nitroxymethyl-6-chloropyridine with β-cyclodextrin, either by kneading the compounds together with a small amount of solvent or by mixing them in an appropriate solvent, such as water. The resulting occlusion compound is then precipitated, separated, and purified using conventional methods.

Career Highlights

Yoshida is associated with Fujisawa Pharmaceutical Company, Ltd., where he has contributed to various research initiatives. His work has been instrumental in advancing pharmaceutical formulations and improving drug delivery systems.

Collaborations

Yoshida has collaborated with notable colleagues, including Yoshio Ueda and Fumio Shimojo. These partnerships have fostered innovation and enhanced the development of new pharmaceutical compounds.

Conclusion

Kiyoshige Yoshida's contributions to pharmaceutical chemistry, particularly through his patented occlusion compound, highlight his role as an innovator in the field. His work continues to influence the development of effective pharmaceutical preparations.