Tokyo, Japan

Kiyoshi Sakai


Average Co-Inventor Count = 3.9

ph-index = 4

Forward Citations = 54(Granted Patents)


Location History:

  • Tokyo, JA (1976 - 1977)
  • Hiromachi, JP (1982)

Company Filing History:


Years Active: 1976-1982

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6 patents (USPTO):Explore Patents

Title: Kiyoshi Sakai: Innovator in Pharmaceutical Chemistry

Introduction

Kiyoshi Sakai is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of innovative compounds with therapeutic applications. With a total of 6 patents to his name, Sakai's work has had a substantial impact on medical science.

Latest Patents

Sakai's latest patents include groundbreaking work on prostacyclin compounds and their derivatives. One notable patent focuses on prostacyclin derivatives of a specific formula, which exhibit excellent thrombocyte agglutination inhibitory, coronary blood vessel dilatory, and bronchodilatory effects. These compounds can be synthesized through a Wittig reaction, introducing a side chain that enhances their pharmaceutical properties. Another significant patent involves 9-oxo-15-hydroxy-20-alkylideneprost-13(trans)-enoic acid derivatives, which are useful as anti-ulcerogenic or bronchodilating agents. The preparation of these compounds involves oxidizing protected hydroxy derivatives, showcasing Sakai's expertise in chemical synthesis.

Career Highlights

Kiyoshi Sakai is currently associated with Sankyo Company, Limited, where he continues to innovate in the pharmaceutical sector. His work has not only advanced the understanding of prostacyclin compounds but has also contributed to the development of new therapeutic agents that can improve patient outcomes.

Collaborations

Sakai has collaborated with notable colleagues such as Takashi Yusa and Shinsaku Kobayashi. These partnerships have fostered a collaborative environment that enhances the research and development of new pharmaceutical products.

Conclusion

Kiyoshi Sakai's contributions to pharmaceutical chemistry through his innovative patents and collaborations highlight his role as a leading inventor in the field. His work continues to pave the way for advancements in medical treatments and therapies.

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