Company Filing History:
Years Active: 2018
Title: Kiwamu Yamagishi: Innovator in Polysaccharide Production
Introduction
Kiwamu Yamagishi is a notable inventor based in Tokyo, Japan. He has made significant contributions to the field of biochemistry, particularly in the production of polysaccharides. His innovative work has led to the development of a unique enzyme that plays a crucial role in modifying polysaccharide structures.
Latest Patents
Kiwamu Yamagishi holds a patent for "Heparosan-glucuronic acid-5-epimerase, and method for producing polysaccharide using same." This invention provides a polypeptide with heparosan-glucuronate 5-epimerase activity, which is essential for producing polysaccharides where hexuronic acid residues have been epimerized. The process involves screening a cDNA library to obtain a DNA sequence encoding the polypeptide. The epimerase specifically acts on glucuronic acid residues of N-acetyl heparosan and/or iduronic acid residues of completely desulfated N-acetylated heparin. The polypeptide is expressed in insect cells, yielding the enzyme necessary for the epimerization process.
Career Highlights
Kiwamu Yamagishi is associated with Seikagaku Corporation, where he continues to advance research in polysaccharide production. His work has implications for various applications in medicine and biotechnology, particularly in the development of therapeutic agents.
Collaborations
He has collaborated with notable colleagues such as Hideo Mochizuki and Kiyoshi Suzuki, contributing to the advancement of their shared research goals.
Conclusion
Kiwamu Yamagishi's innovative work in the field of polysaccharides exemplifies the impact of dedicated research and collaboration in advancing biochemistry. His contributions are paving the way for future developments in this important area of science.