Company Filing History:
Years Active: 1996-2000
Title: Kiran M Khandke: Innovator in Affinity Chromatography
Introduction
Kiran M Khandke is a notable inventor based in Nanuet, NY (US). He has made significant contributions to the field of biotechnology, particularly in the area of affinity chromatography. With a total of 8 patents to his name, Khandke's work has advanced the purification processes of biological materials.
Latest Patents
Khandke's latest patents include an innovative affinity chromatographic matrix that utilizes a non-covalently bound ligand. This matrix is designed for the purification of biological materials, featuring an ionically charged polymeric ligand such as glycoaminoglycan. The ligand is non-covalently bound to the chromatographic matrix through an ionic bond, allowing for easy washing and replacement during subsequent purifications. This method enhances the efficiency of purifying biological materials from crude mixtures. Another significant patent involves mutant strains of Proteus vulgaris that produce chondroitinase I and II proteins without the need for exogenous inducers. These mutants are capable of producing these proteins in greater amounts than their wild-type counterparts, showcasing Khandke's innovative approach to biotechnological challenges.
Career Highlights
Khandke is currently associated with American Cyanamid Company, where he continues to develop and refine his inventions. His work has not only contributed to the scientific community but has also had practical applications in various industries.
Collaborations
Khandke has collaborated with notable colleagues such as John W Gotto and Ursula Eul, further enhancing the impact of his research and innovations.
Conclusion
Kiran M Khandke's contributions to affinity chromatography and biotechnology exemplify the spirit of innovation. His patents reflect a commitment to advancing scientific knowledge and improving purification techniques in biological research.