Kinya Matsuo

Title: Kinya Matsuo and a Cell Culture Method for Blood-Brain Barrier Models.

Introduction

Kinya Matsuo is an inventor associated with Yamaguchi University in Yamaguchi, Japan. His work includes a patent for a cell culture method and device designed to support production of an in vitro, three-layer blood-brain barrier model.

Latest Patents

Matsuo is associated with 1 patent: “Cell Culture Method and Cell Culture Device Used with Cell Culture Method.” The invention describes a process for producing a model containing vascular endothelial cells, pericytes, and astrocytes. The method cultures astrocytes on the outer surface of a porous membrane, then seeds pericytes while the cell culture insert is inverted. It next cultures temperature-sensitive vascular endothelial cells embedded in a temperature-sensitive gel and melts the gel. The approach is intended to facilitate mass production of three-layer blood-brain barrier models in vitro.

Career Highlights

Matsuo’s listed patent focuses on a cell culture technique and device for creating a structured model of the blood-brain barrier. Such models can support laboratory research into interactions among vascular endothelial cells, pericytes, and astrocytes.

Collaborations

Matsuo’s listed coworker is Susumu Fujikawa. The patent information provided associates Matsuo with Yamaguchi University.

Conclusion

Kinya Matsuo’s patent describes a cell culture method intended to make three-layer blood-brain barrier models more practical to produce at scale.