Company Filing History:
4 out of 872 
2 out of 96 Years Active: 2017-2019
Title: Kiho Lee: Innovator in Mammalian Oocyte Activation and Gene Targeting
Introduction
Kiho Lee is a prominent inventor based in Columbia, MO (US), known for his significant contributions to the fields of reproductive biology and genetic engineering. With a total of 4 patents, Lee has made strides in improving the efficiency of artificial oocyte activation and developing gene-targeting vectors for transgenic animals.
Latest Patents
One of Lee's latest patents is focused on artificial oocyte activation. This invention provides novel methods for enhancing the efficiency of artificial activation of unfertilized mammalian oocytes by reducing the intracellular concentration of zinc in the oocyte. The methods may also include a preceding step of increasing the intracellular concentration of calcium in the oocyte prior to the reduction of zinc concentration. Additionally, the invention offers unfertilized oocytes activated by these methods and viable mammalian animals produced from them.
Another significant patent by Lee involves an interleukin-2 receptor gamma gene-targeting vector. This invention relates to a method for producing an immune cell-deficient transgenic cloned miniature pig that has the vector introduced. The implications of this work are substantial for research in immunology and genetic studies.
Career Highlights
Kiho Lee has worked with esteemed institutions such as the University of Missouri and Konkuk University Industrial Cooperation Corporation. His research has been pivotal in advancing the understanding of reproductive technologies and genetic modifications in animals.
Collaborations
Lee has collaborated with notable colleagues, including Randall S. Prather and Jin-Hoi Kim, who have contributed to his research endeavors and innovations.
Conclusion
Kiho Lee's work in artificial oocyte activation and gene targeting represents a significant advancement in biotechnology. His patents not only enhance scientific understanding but also pave the way for future innovations in reproductive and genetic engineering.