The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

Oct. 06, 2017
Applicants:

Kiho Lee, Columbia, MO (US);

Randall S. Prather, Columbia, MO (US);

Inventors:

Kiho Lee, Columbia, MO (US);

Randall S. Prather, Columbia, MO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 15/00 (2006.01); C12N 5/075 (2010.01); A01K 67/027 (2006.01); C12N 15/877 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0609 (2013.01); A01K 67/0273 (2013.01); C12N 15/877 (2013.01); C12N 15/8778 (2013.01); A01K 2227/108 (2013.01); C12N 2500/14 (2013.01); C12N 2500/22 (2013.01); C12N 2501/405 (2013.01); C12N 2517/04 (2013.01); C12N 2517/10 (2013.01);
Abstract

The present invention provides novel methods for improving the efficiency of artificial activation of unfertilized mammalian oocytes by reducing the intracellular concentration of Znin the oocyte. The methods of the invention may additionally comprise a preceding step of increasing the intracellular concentration of Cain the oocyte prior to reduction of the intracellular Znconcentration. The invention further provides unfertilized oocytes activated by the disclosed methods and viable mammalian animals produced from unfertilized oocytes activated by the disclosed methods.


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