Location History:
- Daejon, KR (2011)
- Daejeon, KR (2011 - 2015)
Company Filing History:
2 out of 19 
1 out of 321 
1 out of 87 Years Active: 2011-2015
Title: Kiho Lee: Innovator in Pharmaceutical Compounds
Introduction
Kiho Lee is a notable inventor based in Daejeon, South Korea. He has made significant contributions to the field of pharmaceuticals, particularly in developing compounds that target critical biological pathways involved in cancer and mental health disorders. With a total of 4 patents, his work exemplifies the intersection of innovation and healthcare.
Latest Patents
One of Kiho Lee's latest patents is focused on an aryloxy phenoxy acrylic compound that exhibits HIF-1 inhibition activity. This invention relates to a compound that inhibits HIF-1 activity, a transcription factor crucial for cancer cell growth and metastasis. The compound demonstrates anticancer activity by selectively inhibiting HIF-1, making it a potential therapeutic agent for various solid tumors, including colon, liver, stomach, and breast cancers. Additionally, it may serve as a treatment for diabetic retinopathy and arthritis, conditions exacerbated by hypoxia-induced VEGF expression.
Another significant patent involves phenyl piperazine compounds, which are novel derivatives with high binding affinity for the Serotonin 1A receptor. This invention includes a pharmaceutical composition aimed at treating and preventing depression and anxiety. The piperazine compound is designed to provide an effective treatment for conditions related to the 5-HT1A receptor in mammals.
Career Highlights
Kiho Lee has worked with prominent organizations such as SK Holdings Co., Ltd. and the Korea Research Institute of Bioscience and Biotechnology. His experience in these institutions has allowed him to advance his research and contribute to the development of innovative pharmaceutical solutions.
Collaborations
Throughout his career, Kiho Lee has collaborated with talented individuals, including Yonggil Kim and Nahmryune Cho, who have contributed to his research endeavors.
Conclusion
Kiho Lee's innovative work in pharmaceutical compounds highlights his commitment to addressing critical health challenges. His patents reflect a deep understanding of biological mechanisms and a dedication to improving therapeutic options for patients.