Company Filing History:
Years Active: 2001-2003
Title: Kevin Scott McGuffy: Innovator in Pharmaceutical Formulations
Introduction
Kevin Scott McGuffy is a notable inventor based in Stanhope, NJ (US), recognized for his contributions to pharmaceutical formulations. He holds two patents that focus on advanced drug delivery systems, particularly for metformin hydrochloride and bupropion hydrochloride.
Latest Patents
One of his latest patents is titled "Directly compressible extended-release matrix formulation for metformin hydrochloride." This patent describes an extended-release matrix formulation that can be directly compressed into tablets containing metformin hydrochloride blended with specific excipients. The excipients enhance the flow and compaction properties of the drug, ensuring that the formulation is directly compressible into tablets with dosages ranging from about 100 mg to about 800 mg, preferably between 250 mg and 750 mg. Each tablet produced has the desired hardness and dissolution characteristics, allowing for the drug to be released in the body over an extended period.
Another significant patent is "Methods and formulations for making bupropion hydrochloride tablets using direct compression." This patent outlines methods and formulations for creating extended-release bupropion hydrochloride tablets through direct compression. The tablets combine bupropion hydrochloride with binders such as polyethylene oxide or hydroxypropyl cellulose, along with fillers, glidants, and lubricants. These tablets are designed to be hard, chip-resistant, and exhibit improved cohesiveness, making them easy to form without adhering to the compression punches and dies.
Career Highlights
Throughout his career, McGuffy has worked with Pharmalogix, Inc., where he has contributed to the development of innovative pharmaceutical products. His expertise in drug formulation has made a significant impact in the field of pharmaceuticals.
Collaborations
One of his notable collaborators is Vijai Kumar, with whom he has worked on various projects related to pharmaceutical formulations.
Conclusion
Kevin Scott McGuffy's innovative work in pharmaceutical formulations has led to advancements in drug delivery systems, particularly for metformin and bupropion. His patents reflect a commitment to improving patient outcomes through effective medication delivery.